Patient-Centered Outcomes Research Institute (PCORI)
Patient-Centered Outcomes Research Institute (PCORI) funds patient-centered comparative clinical effectiveness research (CER) that helps people make informed healthcare decisions and improves healthcare delivery and outcomes by producing evidence from research guided by patients, their caregivers and the broader health and healthcare community.
PCORI issues funding opportunity announcements several times each year. PCORI also funds projects that support CER, such as methodology studies, as well as projects that support engagement in research and dissemination and implementation of PCORI-funded research findings.
Use the search/filters below to find available funding opportunities and take advantage of the following resources:
- What & Who We Fund Overview of the type of research PCORI funds
- Research We Fund Description of the elements of patient-centered CER PCORI has funded
- What You Need to Know to Apply Look at the "Decision tree" graphic detailing patient-centered comparative clinical effectiveness (CER) questions to determine if your research fits.
- Funding Opportunities
- Standard Due Dates for 2026 Funding Announcement Cycles
- Applicant Town Halls for Cycle 2 will take place in April. Recordings from the Broad Pragmatic Studies and the PLACER Cycle 1 2026 PCORI Funding Announcement (PFA) webinars are available on the PCORI website.
FUNDING
The PCORI Funding page, www.pcori.org/apply includes the Cycle 2 2026 preannouncements and Engagement Awards funding announcements.
PCORI intends to issue the following PCORI Funding Announcements (PFAs) April 1, 2026. You can view the preannouncements and Applicant Town Halls at the links below:
- Addressing Sensory Health Needs Across the Lifespan PFA. There is a special preannouncement Applicant Town Hall on Jan. 22. Register now.
- Broad Pragmatic Studies, with the following special areas of emphasis:
- Addressing Obesity
- Diabetes Prevention, Care and Treatment
- Management of Urogynecological and Pelvic Pain
- Pain Management for Individuals Living With Sickle Cell Disease
- Phased Large Awards for Comparative Effectiveness Research PFA
- Advancing the Science of Engagement in Research PFA
- Improving Methods for Conducting Patient-Centered Comparative Clinical Effectiveness Research PFA
ENGAGEMENT
- Engagement Award program: https://www.pcori.org/engagement-research/eugene-washington-pcori-engagement-award-program
- Foundational Expectations for Partnerships in Research: https://www.pcori.org/engagement-research/engagement-resources/foundational-expectations
- Other engagement resources that should prove helpful include an engagement resource repository and literature repository.
OTHER INITIATIVES AND OPPORTUNITIES
- Opportunities for merit reviewers: https://www.pcori.org/funding-opportunities/merit-review/become-merit-reviewer
- Advisory panel applications: https://www.pcori.org/about/pcoris-advisory-panels